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In 1998, MSD expanded the MSD MECTIZAN Donation Program to include the prevention of lymphatic filariasis (LF), commonly referred to as elephantiasis, in African countries where the disease co-exists with river blindness.

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Climate change has the potential to alter the average exposure of human populations to vector-borne diseases by changing the geographical distribution of conditions that are suitable for the vectors and disease pathogens.

As a result of the investments and work of many partners, the efforts toward control and elimination of both Onchocerciasis and LF are advancing.

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Acceleration of the reduction in transmission can be achieved either by improving the implementation of annual CDTI, notably increasing CDTI treatment coverage, or by using alternative treatment strategies (ATS) where CDTI cannot be implemented effectively (in particular in areas co-endemic for loiasis), or CDTI effectiveness is considered sub-optimal.

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